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Thickened Ligamentum Flavum – Thickening of this ligament can cause stenosis Spondylosis/Spondylolisthesis – Stress fractures in the spine (Spondylolysis) or Slippage of one vertebra over another (spondylolisthesis) can also cause stenosis

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Management of active disease Pharmacological therapy First-line pharmacotherapy in most patients: NSAIDs Second-line : TNF-α inhibitors (e.g., etanercept, adalimumab)