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In this binge drinking rat model, ADH and ALDH activity were markedly decreased, whereas they were significantly recovered by GSH and GSH-rich YE (Fig
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This process, which was shown to last for several days after initiation, is now discussed as a central pathomechanism in Complex Regional Pain Syndrome (CRPS), a disorder that clinically overlaps with ME/CFS (Cooper and Clark, 2013)
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