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Thus, despite the controlled nature of these trials, they have several shortcomings that have confounded evaluation of the therapeutic potential of DCA in any well-defined population of patients with mitochondrial disease
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[DOI] [PubMed] [Google Scholar] Zamek-Gliszczynski MJ, Hoffmaster KA, Humphreys JE, Tian X, Nezasa KI, and Brouwer KL (2006a) Differential involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in biliary excretion of 4-methylumbelliferyl glucuronide and sulfate in the rat
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