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Desarrollo Este documento ha sido redactado por un comité de expertos utilizando la nomenclatura de la clasificación de la International Headache Society (IHS), analizando la evidencia científica publicada sobre diagnóstico y tratamiento y estableciendo unas recomendaciones prácticas con niveles de evidencia

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In preclinical models, ARA-290 has been observed to shift macrophage polarization from M1 (pro-inflammatory) toward M2 (anti-inflammatory/reparative) phenotypes, suggesting a role in resolution of inflammation and tissue repair signaling