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437,438 The mechanisms by which obesity induces adipose tissue inflammation include increased ROS levels leading to oxidative stress, 439 ER stress activating intracellular inflammatory pathways, 440 free fatty acids activating inflammasomes and pattern recognition receptors, 438 hypoxia and mechanical stress caused by excessive adipocyte expansion

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Chronic gastritis can be classified on the base of the underlying etiologic agent (eg, Helicobacter pylori, bile reflux, nonsteroidal anti-inflammatory drugs [NSAIDs], autoimmunity, allergic response) and the histopathologic pattern, which may suggest the etiologic agent and clinical course (eg, H pylori –associated multifocal atrophic gastritis)