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Genetic and Mechanistic Insights Inform Amyotrophic Lateral Sclerosis Treatment and Symptomatic Management: Current and Emerging Therapeutics and Clinical Trial Design Considerations | CNS Drugs | Springer Nature Link
A particular mutation, V617F, is thought to make cells in hematopoietic (developmental) phases more sensitive to erythropoietin and thrombopoietin, two growth factors that are produced in the kidney, with thrombopoietin also being produced in the liver
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