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Proband The patient who is the initial member of the family to come under investigation for a medical condition
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Individuals specifically at risk for low B9 (folate) or B12 vitamin status and having high Hcy levels are as follows: Those who have a high alcohol intake, smokers, those with a personal/family history of premature cardiovascular disease, malnutrition/malabsorption syndromes, hypothyroidism, kidney failure, and lupus
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