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Hashimoto's thyroiditis | Hashimoto's disease – Symptoms & Causes

This finding suggests that βarr1–Src interactions are broadly distributed, and that the mutations tested, while disruptive, are not sufficient to fully abolish βarr-mediated Src activation

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In mammalian cells, it triggers mitochondrial membrane disruption and cytochrome C release, subsequently inducing cell apoptosis 49,50