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Antioxidant and anti-inflammatory signalling: Published research has shown interactions with antioxidant defence systems and inflammatory signalling pathways in laboratory models, including modulation of pro-inflammatory cytokine activity and upregulation of antioxidant enzyme expression

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The condition is characterized by elevated anti-thyroid peroxidase (anti-TPO) and anti-thyroglobulin antibodies, lymphocytic infiltration of thyroid tissue, and gradual development of hypothyroidism