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As gut microbiota have an undeniable impact on intestinal mucosa integrity and immune system function, there have been attempts in progress to modify a microbiome in several autoimmune diseases, including HT

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PPO activity was measured using the molar extinction coefficient 3400 mM -1 cm -1 , and expressed as nmol of catechol oxidized per min per g FW (nM min -1 g -1 FW)