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Indeed, it has been proposed that the appearance of ascorbate was an important factor in the development of multicellular organisms because of its antioxidant role but also in the function of 2-ODDs in extracellular matrix protein synthesis and epigenetic control of stem cell activity (Edgar, 2019)

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Our findings indicate that the thermal decomposition of P(4HB) yields a series of cyclic oligomers (i.e., gamma-butyrolactone and its higher homologs) by an intramolecular exchange mechanism