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Autocrine GH enhances cell viability, clonogenic survival, and DNA repair in breast and endometrial cancers after ionizing radiation (Wu et al., 2014), whereas the over-expression of GHR in rectal cancer is predictive factor for tumor response to preoperative radiotherapy (Wu et al., 2006)

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It acts more like a system-wide signal — touching multiple pathways at once, which is part of why its effects are so broad and, honestly, a bit unusual for something this small