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This chromosomal protection occurs both in normal aging and in conditions of accelerated oxidative stress, indicating broad-spectrum antioxidant defense enhancement

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469 The mitochondrial protein sideroflexin 1 (SFXN1) is responsible for importing iron from the cytoplasm to the mitochondria, and SFXN1 deficiency leads to mitochondrial respiratory chain damage, affecting the biogenesis and assembly of complex III