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The combined analysis revealed that mung bean polyphenols, vitexin, orientin, and caffeic acid almost all resulted in the downregulation of HSP70 mRNA content at each heat stress temperature compared to the control group
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nevertheless, given that the current evidence stems primarily from small, nonrandomized cohort studies, the efficacy, optimal target populations, and long-term safety of this treatment must be further investigated through prospective, controlled studies based on standardized protocols 177
