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CLINICAL MANIFESTATIONS OF β THALASSEMIA SYNDROMES Mutations causing thalassemia can affect any step in the pathway of globin gene expression: transcription, processing of the mRNA precursor, translation, and posttranslational metabolism of the β-globin polypeptide chain

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The MHRA position on unlicensed peptides used systemically has been clear and was repeated in coverage by The Guardian and the BBC during 2025 and 2026