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In the United States, real-time genomic surveillance programs for foodborne pathogens have been developed in the last decade to support food safety and public health, including the GenomeTrakr program operated by the Food and Drug Administration (FDA) and the PulseNet program coordinated by the CDC (126, 155)
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However, whereas one published case report noted a response of RMC to anti-PD-1 immune checkpoint therapy (ICT) with nivolumab 11 , two additional case reports suggested poor efficacy of nivolumab alone or in combination with anti-CTLA-4 blockade using ipilimumab 12
