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GHR growth hormone receptor, SSTN somatostatin, PRLR prolactin receptor, PRL prolactin, JAK-2 Janus kinase 2, STAT signal transducer and activator of transcription, MAPK mitogen-activated protein kinase, PI3K/AKT/mTOR phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin Cancer There is a growing body of evidence that implicates GH in multiple cancer types, particularly breast, colon and endometrial cancer

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Drugs absorbed from suppositories in the lower rectum enter vessels that drain into the inferior vena cava, thus bypassing the liver