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If there is poor GSH synthesis due to low cysteine levels, inadequate GCL enzyme, inadequate GSH synthetase, or mutations in GCLC or GCLM, then we can expect to see problems in the reduction of peroxides and a resultant increase in free oxygen radicals

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43 , 44 To summarize, among the four major NADPH-producing pathways we have discussed, the PPP is generally considered as the most important source to provide cytosolic NADPH

Glutathione is also beneficial for promoting heart and cardiovascular health