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The genetic correlates relate primarily to variants in the genes coding for transporters controlling plasma UA, yet such presumed functional variants will also influence, through the same proteins, the transport of UA into the brain and subsequently into neurons and glia, as described below
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Groups with Higher Needs or Risks [10] : Pregnancy & Lactation: Marginal biotin deficiency occurs in up to one-third of pregnant women and is also seen in lactating women, even with normal intake
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