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In a chronic sciatic nerve compression model, depression-like behaviors and microglial activation with TNF-α upregulation in the medial prefrontal cortex, hippocampus, and amygdala emerged only after 8 weeks, despite allodynia occurring immediately after chronic constriction injury (Barcelon et al., 2019)
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It is a coordination complex: a three-residue human sequence, glycyl-L-histidyl-L-lysine, bound to a copper(II) ion through a defined set of donor atoms
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