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Clinical Implications Irritable Bowel Syndrome Differently from IBD and celiac disease, IBS is not associated with overt mucosal inflammation, and evidence supporting the potential role of cytokines in these patients has been so far controversial (Figure 2) (219–221)

Mecobalamin

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Role of the tight junction in the esophagus and related diseases Food travels through the esophagus from the pharynx to the stomach