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315 Moreover, H3K18la promotes early growth response 1 (EGR1) transcription, with increased lactylation of EGR1 at lysine 364, enhancing its nuclear localization by binding with importin-α, eventually leading to heparinase upregulation and glycocalyx degradation in pulmonary microvascular ECs during S-ALI

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Timing Baseline Marker CRP Why it matters Can provide a general inflammation trend, although it does not show whether a local tendon or ligament is healing