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In this study, we present a novel standardized peripheral nerve transection method in mice using fibrin glue for modeling peripheral nerve transection injury with reproducible gap distance between the severed nerve ends

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This occurs in peripheral circulation and can promote symptoms such as postural orthostatic tachycardia syndrome (PoTS), PEM, fatigue, endothelial cell dysfunction, platelet hyperactivation, mast cell activation, and connective tissue disorders