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Coupled with surgical treatment is chemoradiation that combines six weeks of IR, delivering 60 Gy in 30 fractions to residual disease with daily TMZ (4), followed by six months of adjuvant TMZ using a 5-day over 28-day schedule (5)

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Added limitations that need to be addressed include the extended timeline for developing autologous CAR-T cell repertoire and the high cost of CAR-T therapy

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