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Careful monitoring and observation of this cell-based therapy are of paramount importance, since evidence has shown that adipose-derived MSCs have lost genetic stability over time and were prone to tumor formation.[43] Based on the specific application, SC should be differentiated into appropriate cell types before they can be clinically used, failure of which may have deleterious effects

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However, it was unknown whether mitochondrial-encoded peptide treatment regulates proinflammatory immune cells to prevent autoimmune disease, such as T1DM