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Second, we provide a systematic and updated overview of glial contributions, highlighting emerging evidence that microglia act as primary drivers of iron-mediated neurotoxicity, and that astrocytes undergo dynamic phenotypic shifts regulated by pathways such as mTOR and CSE/YAP/FOXD3 mechanisms that modulate neuronal vulnerability in previously underappreciated ways

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[DOI] [PubMed] [Google Scholar] 739.Piazza I., Kochanowski K., Cappelletti V., Fuhrer T., Noor E., Sauer U., Picotti P

oxidized glutathione (GSH/GSSG) ratio serves as an indicator of oxidative stress