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Vitamin A Vitamin A, in its active form as all-trans-retinoic acid (ATRA), plays a crucial role in antioxidant defense mechanisms in the skin, particularly through its impact on melanocytes and modulation of oxidative stress

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Importantly, REDEFINE 1 also showed that a significant proportion of participants achieved ≥25% body weight reduction — a threshold that, in clinical terms, represents the kind of weight loss previously achievable only through bariatric surgery