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doi: 10.1016/S0140-6736(19)33005-3 57 BrittRDJr.ThompsonMASasseSPabelickCMGerberANPrakashYS

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As a key protease in the clear apoptosis pathway, its absence or downregulation is associated with carcinogenic effects, indicating its potential as a biomarker for cancer prevention and treatment [93]