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This diffusible intracellular 2nd messenger in turn is an activating ligand for the cytoplasmic enzyme, cAMP-dependent protein kinase (PKA)

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Lung We noted, in the control rats, the thickening of the alveolar membranes due to capillary congestion, pulmonary edema, and dilatation of larger blood vessels in all three assessment time periods (15 min, 30 min, and 60 min following laurate application)