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The risks of self-injection with "home kits" are too significant to ignore: Improper Injection Technique: Without proper training, you could cause pain, bruising, infection, nerve damage, or inject the medication incorrectly, making it less effective

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They showed the significant upregulation of IL-1b mRNA, tumor necrosis factor (TNF), matrix metalloproteinases MMP-3 (30x increase), MMP-13 (7x), and the tissue inhibitor of metalloproteinases- (TIMP-) 1 (4x) in the FQ-treated rats