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I was educated on the scientific method. Evidence based medicine became the cornerstone of practice during my years as a resident. What has changed? Many factors and no right answer but before

I feel stronger and have less of the afternoon tiredness that I had before

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Broadly, many patients notice improved energy and reduced fatigue within 1 to 2 weeks of starting intramuscular injections, while full neurological symptom resolution can take several weeks to months depending on deficiency severity