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In contrast, there is a report demonstrating that the non-oxidative form of dopamine can inhibit erastin-induced ferroptosis (Wang et al., 2016)
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In this context, effective iron-chelating drugs can enhance the immune function against cancer cells by reducing the iron load of macrophages and other cells of the immune system, which, for example, has been previously shown in iron-loaded patients [18,173,174,175,176,177,178,179,180,181]