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IL-10 has an immunoregulatory function and mainly acts as an immunosuppressive cytokine

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Crujeiras, Pissios, Moreno-Navarrete, and colleagues, writing in Molecular Nutrition and Food Research in 2018, identified an epigenetic signature in human adipose tissue linked to NNMT gene expression, reinforcing the idea that the methylation axis is a live variable in human fat biology rather than a rodent-only phenomenon