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34 Hence, it may be preferable to collect surgical specimens in this species, and this approach gives the added advantage that other organs can be sampled (e.g., liver and pancreas) when checking for “triaditis.” The standards published by the WSAVA GI Standardization Group 2 hopefully will improve the reliability of IBD diagnosis.18, 28 Ultimately, the primary clinician should interpret histopathology results cautiously and try to relate them to the clinical presentation

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Key Takeaways MOTS-c activates AMPK to increase fat oxidation and mitochondrial biogenesis, with a half-life of 4–6 hours requiring multiple weekly doses