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Likewise, with the suspension of supplements, the experimental group showed a reduced incidence of secondary neoplasms (39/1000 versus 69/1000, HR = 0.57, 95% CI = 0.31 to 1.0), and it was significantly lower when α-tocopherol was the only supplement (HR = 0.41, 95% CI = 0.16 to 1.03) (20)

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