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The anti-ferroptotic potential of other synthetic phenolic compounds, such as 1,8-tetrahydronaphthyridinols has been demonstrated, where the inherent radical-trapping antioxidant reactivity of 1,8-tetrahydronaphthyridinols was similarly effective as ferrostatin-1 and liproxstatin-1 at subverting ferroptosis triggered by either genetic or pharmacological inhibition of the hydroperoxide-detoxifying enzyme GPX4 in mouse fibroblasts and hippocampal cells (81)
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doi: 10.1042/BJ20031049
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![PDF] A Novel Natural NADH and NADPH Dependent Glutathione Reductase as Tool in Biotechnological Applications](https://figures.semanticscholar.org/eca758e0922bca0c9b317a6cdb6afb313559d24d/3-Figure1-1.png)
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