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It has been shown that DCE-MRI can detect responses to PTK/ZK (a VEGF receptor tyrosine kinase inhibitor) therapy as early as two days after therapy with significant reductions in area under gadolinium-contrast-medium curve (AUGC) (30) or permeability parameters (188), which also predict subsequent response
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There was no presence of anti-AOD9604 antibodies detected, and no serious side effects were noted
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