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In turn, the promotion of autophagy through the downregulation of hyperactive mTORC1 signaling by upregulating calcium and integrin binding protein 2 (CIB2) and the activation of the proliferator-activated receptor gamma coactivator 1 (PGC-1) [252] and AMPK-mTOR [253] signaling pathways have shown significant potential as novel therapies for dry and wet AMD [254,255]

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Localization and role of NPC1L1 in cholesterol absorption in human intestine