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However, the process of reconstituting lyophilized powders adds potential for patient error, and supply chain complexity

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For weight management, NICE has appraised several licensed medicines that are available through NHS pathways or regulated private clinics: Semaglutide (Wegovy) — NICE Technology Appraisal TA875 recommends semaglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m² or more (or 30–34.9 kg/m² in certain circumstances) alongside at least one weight-related comorbidity, when used within a specialist weight management service