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The recent crystal structure of the entire extracellular domain of CaSR (Geng et al., 2016) identified four novel Ca 2+ binding sites in each protomer of the homodimer including one at the homodimer interface which does not correspond to any of the sites reported previously by Huang et al., (2007)

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Zhang W, Ly C, Zhang Q, Mu H, Battula VL, Patel N, Schober W, Han X, Fogler WE, Magnani JL, Andreeff M