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RBDs from SARS-CoV-2, SARS-CoV-1, bat CoV RaTG13, and bat CoV WIV1 were genetically fused using linkers to I53-50A, allowing the display of 60 RBDs in a trimeric form in a vaccine named RBD-NP or GBP511 [145] (Table 2)
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Despite the widespread adoption of rigorous public health measures such as social distancing, personal care, mask mandates, and lockdowns, the virus continues to proliferate, escalating infections and fatalities worldwide