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Recently, it has been confirmed in a population-based study that there is a modest increase in both the absolute fracture risks (12.5 per 1000 person-years for any fracture, and 1.9 per 1000 person-years and 3.4 per 1000 person-years for hip fracture and for ulna/radius fracture, respectively) and the relative fracture risks (approximately 2-fold increased) in patients with PBC, with the excess risk similar in those with more severe disease [167]

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