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This finding also emphasizes the importance of the biliary excretion as a first step in complex multiorgan pathways involved in glutathione S -conjugate and cysteine S -conjugate metabolism (Dekant et al., 1994)

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We found that compared to vitamin C or glutathione single supplementation, acute vitamin C and glutathione complex supplementation in 12 middle-aged triathletes resulted in decreased carbon dioxide output, decreased heart rate, and positive improvements in skeletal muscle oxygenation during 90 min of cycling exercise at 70% VO 2max , as well as positive improvements in blood and biological antioxidant potential (BAP) and diacron reactive oxygen metabolite(dROM) [85]