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Inflammatory stimuli such as LPS downregulate the expression of these proteins through the TLR4/NF-κB and myosin light chain kinase (MLCK)/myosin light chain (MLC) signaling pathways, while sulforaphane (SA) can restore TJ protein expression and barrier function by inhibiting both pathways [70]

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Phosphorylation-Assisted Luciferase Complementation Assay Designed to Monitor Kinase Activity and Kinase-Domain-Mediated Protein-Protein Binding