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Given that GCL or GGT pharmacological inhibition or silencing effectively blocks the growth of lymphoid tumor cells in 3D gels, including TIC-like cells, we propose that high glutathione levels in the minority of tumor cells that thrive in 3D gels counteract ROS-induced cell death

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mGluRs induce a long-term depression in the ventral tegmental area that involves a switch of the subunit composition of AMPA receptors