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Subsequent post hoc analysis demonstrated a significant reduction in mean MOG expression in slices treated with CPZ in comparison to untreated slices (Untreated: 100% ± 8.5%, CPZ-treated: 53.08% ± 2.52%, p = 0.00002)

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Angiogenic programming of neoplastic tissue is a multidimensional process regulated by cancer cells in concert with a variety of tumour-associated stromal cells and their bioactive products, which encompass cytokines and growth factors, the extracellular matrix and secreted microvesicles