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Randomised, prospective, placebo-controlled trials are needed to further evaluate the efficacy of different treatment approaches

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Benign Prostatic Hyperplasia (BPH) Benign prostatic hyperplasia (BPH) is the pathological progression of epithelial and stromal proliferation in the prostate gland with aging and is one of the most prevalent and costly benign neoplasms in men [1,2,3] (Figure 1), with over 94 million cases worldwide in 2019, compared to 51.1 million cases in 2000 [3]