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In order to be taken up by the liver it has to be degraded to amino acids.” [I also wonder- since glutamate is elevated in metabolic disease, and a residue in the GSH tripeptide, might it be that providing glycine or serine to support synthesis could be preferred over glutathione

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Furthermore, transcription regulation of the antioxidant response ( cAPX, G-POD and GR ) was significantly increased under the HT+GSH treatment, which suggests that antioxidant adjustment in supra-optimal temperature is very important for plant adaptation to heat stress 5