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Therefore, a study has been undertaken to screen the presence of insecticide contamination in the river Teesta and the evaluation of their adverse effects on the non-target organism, Pethia conchonius using the parameters such as micronuclei, comet (Single-cell gel electrophoresis), antioxidant and cholinergic enzyme activity (SOD, CAT, GST, and AChE) and malonaldehyde (MDA) assays followed by pesticide-induced modulation of some antioxidant gene expression, to know the oxidative stress and DNA damage along with altered cholinergic neurotransmission
