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The discovery of CYP51A1 dates back to the mid-1970s, when studies using radiolabeled lanosterol in yeast and rat liver microsomes demonstrated the release of [14 C] formic acid, enabling a straightforward assay of lanosterol 14α-demethylase activity across species [10]
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Dieses ist gerade deshalb fatal, weil die Gabe von Statinen nicht nur die Cholesterin-, sondern auch die Coenzym Q10-Synthese hemmt
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